主な論文2021年度

Thesis

雪印メグミルク研究報告

2021年度内容

乳酸菌と体脂肪低減作用（ガセリ菌SP株の例を中心に）
The effect of lactic acid bacteria on human adiposity

掲載誌：
乳業技術, 70, 75-85, (2020)
著　者：
浮辺健
所　属：
雪印メグミルク株式会社　ミルクサイエンス研究所

ガセリ菌SP株の内臓脂肪低減作用

掲載誌：
Functional food, 40, 15(1), 38-42, (2021)
著　者：
塚原拓也、木村彰
所　属：
雪印メグミルク株式会社　ミルクサイエンス研究所

Effector memory CD4+T cells in mesenteric lymph nodes mediate bone loss in food-allergic enteropathy model mice, creating IL-4 dominance

掲載誌：
Mucosal Immunooogy, 14(6), 1335-1346, (2021)
著　者：
Aiko Ono-Ohmachi1,2, Satoki Yamada3, Satoru Uno3, Masato Tamai3, Kohei Soga3, Shotaro Nakamura3, Nobuyuki Udagawa4, Yuko Nakamichi5, Masanori Koide5, Yoshikazu Morita1, Tomohiro Takano3, Takumi Itoh6,7, Shigeru Kakuta8, Chikao Morimoto6, Shuji Matsuoka9, Yoichiro Iwakura10, Michio Tomura11, Hiroshi Kiyono12,13,14, Satoshi Hachimura3 and Haruyo Nakajima-Adachi3,12
所　属：
  1. 1Milk Science Research Institute, Megmilk Snow Brand Co., Ltd.
  2. 2Department of Quality Assurance, Bean Stalk Snow Co., Ltd.
  3. 3Research Center for Food Safety, Graduate School of Agricultural and Life Sciences, The University of Tokyo
  4. 4Department of Biochemistry, Matsumoto Dental University
  5. 5Institute for Oral Science, Matsumoto Dental University
  6. 6Department of Therapy Development and Innovation for Immune Disorders and Cancers, Juntendo University
  7. 7Atopy (Allergy) Research Center, Graduate School of Medicine, Juntendo University
  8. 8Laboratory of Biomedical Science, Graduate School of Agricultural and Life Sciences, The University of Tokyo
  9. 9Department of Immunological Diagnosis, Graduate School of Medicine, Juntendo University
  10. 10Research Institute for Biomedical Sciences, Tokyo University of Science
  11. 11Laboratory of Immunology, Faculty of Pharmacy, Osaka Ohtani University
  12. 12IMSUT Distinguished Professor Unit, Division of Mucosal Immunology, The Institute of Medical Science, The University of Tokyo
  13. 13Mucosal Immunology and Allergy Therapeutics, Future Medicine Education and Research Organization, Institute for Global Prominent Research, Graduate School of Medicine, Chiba University
  14. 14Division of Gastroenterology, Department of Medicine, School of Medicine, CU-UCSD Center for Mucosal Immunology, Allergy and Vaccines, University of California

Bone mass protective potential mediated by bovine milk basic protein requires normal calcium homeostasis in mice

掲載誌：
Nutrition,Volumes 91–92, November–December 2021, 111409
著　者：
Aiko Ono-Ohmachi1,2, Yuko Ishida1, Yoshikazu Morita1, Ken Kato1, Hitoki Yamanaka3, Ritsuko Masuyama4,5
所　属：
  1. 1Milk Science Research Institute, Megmilk Snow Brand Co., Ltd.
  2. 2Department of Quality Assurance, Bean Stalk Snow Co., Ltd.
  3. 3Research Center for Support to Advanced Science, Shinshu University
  4. 4Department of Molecular Bone Biology, Nagasaki University Graduate School of Biomedical Sciences
  5. 5Ritsumeikan University, Graduate school of Gastronomy Management

アミノ酸ラセマーゼ遺伝子の制限酵素断片長多型に基づくLactobacillus gasseri/paragasseri の迅速識別法
A New Rapid Method to Differentiate Lactobacillus gasseri from Lactobacillus paragasseri Based on Restriction Fragment Length Polymorphisms of Amino Acid Racemase Genes

掲載誌：
日本食品科学工学会誌, 68(9), 375-379, (2021)
著　者：
加田茂樹、阿部萌子、木村彰
所　属：
雪印メグミルク株式会社　ミルクサイエンス研究所
要　約：
乳酸菌の1種ラクトバチルスガセリは、近年分類の見直しが実施され、その一部がラクトバチルスパラガセリとして再分類された。これら2菌種のアミノ酸ラセマーゼ遺伝子の塩基配列は菌種特有であり、それらを制限酵素で切断してそのパターンを確認することにより迅速にこれら2菌種を識別することが可能な方法を開発した。

Effects of different gases on foaming properties of protein dispersions prepared with whipped cream dispenser

掲載誌：
Journal of Food Engineering, 314, 110764, (2022)
著　者：
Ai Satoa, Kentaro Matsumiyaa, Tatsuya Kosugib, Hiroaki Kubouchib,c, Yasuki Matsumuraa
所　属：
  1. aLaboratory of Quality Analysis and Assessment, Division of Agronomy and Horticultural Science, Graduate School of Agriculture, Kyoto University
  2. bMilk Science Research Institute, Megmilk Snow Brand Co, Ltd.
  3. cProducts Development Department, Megmilk Snow Brand Co, Ltd.

Effects of the thermal denaturation degree of a whey protein isolate on the strength of acid milk gels and the dissociation of κ-casein

掲載誌：
Journal of Dairy Research, 89(1), 104-108, (2022)
著　者：
Daiki Oka1, Wataru Ono2, Shojiro Tamaki3, Tomohiro Noguchi2 and Katsumi Takano1
所　属：
  1. 1Department of Agricultural Chemistry, Tokyo University of Agriculture
  2. 2Food Processing Technology Center, Faculty of Applied Bioscience, Tokyo University of Agriculture
  3. 3Milk Science Research Institute, Megmilk Snow Brand Co., Ltd.

Cohort profile: Japanese human milk study, a prospective birth cohort: baseline data for lactating women, infants, and human milk macronutrients

掲載誌：
BMJ Open 2021;11:e055028
著　者：
Keisuke Nojiri1, Satoshi Higurashi1, Tomoki Takahashi1, Yuta Tsujimori1, Shunjiro Kobayashi2, Yasuhiro Toba1, Jun-ichi Yamamura2, Kyoko Nomura3, and Hiroshi M. Ueno2
所　属：
  1. 1Department of Research and Development, Bean Stalk Snow Co., Ltd.
  2. 2Megmilk Snow Brand Co., Ltd.
  3. 3Department of Environmental Health Science and Public Health, Akita University Graduate School of Medicine